Immunomodulating and antiviral agent.
Stimulates the production of α, β, and γ interferons in the body. Activates bone marrow stem cells; in a dose-dependent manner enhances antibody formation, reduces the degree of immunosuppression, and restores the ratio of T-suppressors to T-helpers. Effective against a broad spectrum of viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis A, B, C, and herpesviruses.
The antiviral mechanism of action is associated with inhibition of the translation of virus-specific proteins in infected cells, thereby suppressing viral replication.
Studies on animals (chicken and duck embryos) demonstrated high antiviral activity of the drug against the highly pathogenic avian influenza (HPAI) virus strain H5N1, as well as significant immunostimulatory and adjuvant activity against HPAI antigens (in chicken studies).
Trade name: AMIXIN® IC
INN: tilorone
Chemical name: dihydrochloride 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one
Dosage form: film-coated tablets 0.06 g and 0.125 g
Pharmacotherapeutic group: antiviral agents for systemic use. Direct-acting antivirals. Tilorone. ATC code J05AX19.
Registration numbers: UA/2559/01/01; UA/2559/01/02
Date of registration / valid until: the marketing authorization is valid indefinitely as of 17.10.2019
Registration in other countries: none
Packaging: tablets No. 3 (3×1), No. 6 (2×3), No. 9 (3×3), No. 10 (5×2) in blister packs in a carton
Shelf life: 5 years
Dispensing category: over-the-counter
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